Lisa Tussing-Humphreys, PhD, MS, RD

Assistant Professor of Medicine

Dr. Tussing-Humphreys is assistant professor in the Division of Academic Internal Medicine and Geriatrics of the Department of Medicine in the University of Illinois at Chicago College of Medicine. She directs the UI Cancer Center's Diet and Behavior Shared Resource, which supports the integration of behavioral and psychosocial factors into UICC research protocols. She also is an associate in the UIC Building Interdisciplinary Research Careers in Women’s Health and an IHRP Fellow.

Her current work focuses on obesity-associated iron metabolism dysfunction and its relationship to health status and disease risk.

A registered dietitian, Dr. Tussing-Humphreys earned her doctoral degree in human nutrition from the UIC College of Applied Health Sciences in 2009, writing her dissertation on hepcidin-mediated iron deficiency of obesity. She holds an MS in nutritional sciences from the University of Illinois at Urbana-Champaign and a BS in clinical dietetics from SUNY College at Buffalo. Before returning to UIC in 2012, Dr. Tussing-Humphreys was research scientist with the USDA Agricultural Research Service, and principal investigator of a church-based diet and physical activity intervention for African American adults in the Lower Mississippi Delta region.

Research Interests

Obesity, inflammation and nutrient metabolism dysfunction, inflammation and cancer, iron in health and disease, intestinal cancers, dietary interventions, dietary assessment, women’s health, health disparities.

Recent and Noteworthy Publications

For links to abstracts of works by Dr. Tussing-Humphreys, see this edited list on PubMed.

Springfield S, Odoms-Young A, Tussing-Humphreys L, Freels S, Stolley M. Adherence to American Cancer Society and American Institute of Cancer Research dietary guidelines in overweight African American breast cancer survivors. J Cancer Surviv. 2019 Apr;13(2):257-268. doi: 10.1007/s11764-019-00748-y. [See abstract]

Hughes SL, Tussing-Humphreys L, Schiffer L, Smith-Ray R, Marquez DX, DeMott AD, Berbaum ML, Fitzgibbon ML. Fit & Strong! Plus Trial Outcomes for Obese Older Adults with Osteoarthritis. Gerontologist. 2018 Nov 26. doi: 10.1093/geront/gny146. [See abstract]

Tussing-Humphreys LM, Thomson JL, Hemphill NO, Goodman MH, Landry AS. Maternal weight in the postpartum: results from the Delta healthy sprouts trial. Matern Health Neonatol Perinatol. 2017;3:20. Published 2017 Dec 4. doi:10.1186/s40748-017-0058-9. [See abstract

Tussing-Humphreys L, Lamar M, Blumenthal JA, et al. Building research in diet and cognition: The BRIDGE randomized controlled trial. Contemp Clin Trials. 2017;59:87–97. doi:10.1016/j.cct.2017.06.003. [See abstract

Thomson JL, Tussing-Humphreys LM, Goodman MH, Landry AS, Olender SE. Low rate of initiation and short duration of breastfeeding in a maternal and infant home visiting project targeting rural, Southern, African American women. Int Breastfeed J. 2017;12:15. Published 2017 Apr 8. doi:10.1186/s13006-017-0108-y. [See abstract

Buscemi J, Miguel YS, Tussing-Humphreys L, et al. Rationale and design of Mi-CARE: The mile square colorectal cancer screening, awareness and referral and education project. Contemp Clin Trials. 2017;52:75–79. doi:10.1016/j.cct.2016.11.009. [See abstract

Thomson JL, Tussing-Humphreys LM, Goodman MH, Zoellner JM. Engagement indicators predict health changes in a lifestyle intervention. Am J Health Behav. 2015 May;39(3):409-20.[See abstract.]

Thomson JL, Goodman MH, Tussing-Humphreys L. Diet quality and physical activity outcome improvements resulting from a church-based diet and supervised physical activity intervention for rural, southern, African American adults: Delta Body and Soul III. Health Promot Pract. 2015 Sep;16(5):677-88.[See abstract]

Koenig MD, Tussing-Humphreys L, Day J, Cadwell B, Nemeth E. Hepcidin and Iron Homeostasis during Pregnancy. Nutrients. 2014 Aug 4;6(8):3062-83.[See abstract.]

Thomson JL, Tussing-Humphreys LM, Goodman MH. Delta Healthy Sprouts: A randomized comparative effectiveness trial to promote maternal weight control and reduce childhood obesity in the Mississippi Delta. Contemp Clin Trials. 2014 May;38(1):82-91. [See abstract.]

Tussing-Humphreys LM, Thomson JL, Onufrak SJ. A church-based pilot study designed to improve dietary quality for rural, Lower Mississippi Delta, African American adults. J Relig Health. 2015 Apr;54(2):455-69.[See abstract.]

Smith-Ray RL, Fitzgibbon ML, Tussing-Humphreys L, Schiffer L, Shah A, Huber GM, Braunschweig C, Campbell RT, Hughes SL. Fit and Strong! Plus: Design of a Comparative Effectiveness Evaluation of a Weight Management Program for Older Adults with Osteoarthritis. Contemp Clin Trials. 2014 Mar;37(2):178-88. [See abstract.]

Tussing-Humphreys L, Thomson JL, Zoellner JM. Psychosocial predictors of diet and physical activity in African-Americans: results from the Delta Body and Soul effectiveness trial, 2010-2011. Am J Health Promot. 2014 Jan-Feb;28(3):e81-91.[See abstract.]

Tussing-Humphreys L, Thomson JL, Mayo T, Edmond E. A church-based diet and physical activity intervention for rural, lower Mississippi delta african american adults: Delta Body and Soul effectiveness study, 2010-2011. Prev Chronic Dis. 2013 Jun 6;10:E92.[See abstract.]

Tussing-Humphreys LM, Fitzgibbon ML, Kong A, Odoms-Young A. Weight loss maintenance in African American women: a systematic review of the behavioral lifestyle intervention literature. J Obes. 2013;2013:437369. [See abstract.]

Thomson JL, Tussing-Humphreys LM, Martin CK, Leblanc MM, Onufrak SJ. Associations among school characteristics and foodservice practices in a nationally representative sample of united states schools. J Nutr Educ Behav. 2012 Sep;44(5):423-31.[See abstract.]

Tussing-Humphreys L, Pusatcioglu C, Nemeth E, Braunschweig C. Rethinking iron regulation and assessment in iron deficiency, the anemia of chronic disease, and obesity: introducing hepcidin. J Am Diet Assoc. 2012;112(4):506-517.[See abstract.]

Fitzgibbon ML, Tussing-Humphreys LM, Porter JS, Martin IK, Odoms-Young A, Sharp LK. Weight loss and African-American women: a systematic review of the behavioural weight loss intervention literature. Obes Rev. 2012;13(3):193-213. Review. [See abstract.]

Thomson JL, Tussing-Humphreys LM, Onufrak SJ, Zoellner JM, Connell CL, Bogle ML, Yadrick K. A simulation study of the potential effects of healthy food and beverage substitutions on diet quality and total energy intake in Lower Mississippi Delta adults. J Nutr. 2011;141(12):2191-2197.[See abstract.]

Thomson JL, Tussing-Humphreys LM, Onufrak SJ, Connell CL, Zoellner JM, Bogle ML, Yadrick K. Simulated reductions in consumption of sugar-sweetened beverages improves diet quality in Lower Mississippi Delta adults. Food Nutr Res. 2011;55.[See abstract.]

Tussing-Humphreys L, Braunschweig C. Anemia in postmenopausal women: dietary inadequacy or nondietary factors? J Am Diet Assoc. 2011;111(4):528-31.

Tussing-Humphreys L, Pini M, Ponemone V, Braunschweig C, Fantuzzi G. Suppressed cytokine production in whole blood cultures may be related to iron status and hepcidin and is partially corrected following weight reduction in morbidly obese pre-menopausal women. Cytokine. 2011;53(2):201-6.[See abstract.]

Tussing-Humphreys L, Frayn KN, Smith SR, Westerman M, Dennis AL, Nemeth E, Thomson J, Pusatcioglu C. Subcutaneous adipose tissue from obese and lean adults does not release hepcidin in vivo. Scientific World J. 2011;11:2197-206.[See abstract.]

Tussing-Humphreys L, Nemeth E, Fantuzzi G, Freels S, Holterman A, Galvani C, Ayloo S, Vitello J, Braunschweig C. Decreased serum hepcidin, inflammation, and improved functional iron status in obese pre-menopausal women six-months post-restrictive bariatric surgery. Obesity. 2010;18(10):2010-2016.[See abstract.]

Wang Y, Jahns L, Tussing-Humphreys L, Xie B, Rockett H, Liang H, Johnson L. Dietary intake patterns of low-income urban african-american adolescents. J Am Diet Assoc. 2010;110(9):1340-1345.[See abstract.]

Tussing-Humphreys L, Nemeth E, Fantuzzi G, Freels S, Guzman G, Holterman A, Braunschweig C. Elevated systemic hepcidin and iron depletion in obese pre-menopausal females. Obesity. 2010;18(7):1449-1456.[See abstract.]

Honors and Awards

IHRP Fellow