Denise M. Hynes, PhD, MPH, RN

Professor of Public Health in Medicine

Dr. Hynes is a professor in the Division of Academic Internal Medicine and Geriatrics in the Department of Medicine, UIC College of Medicine, and a research scientist in the Division of Health Policy Administration of the School of Public Health. Dr. Hynes is also the director of the Biomedical Informatics (BI) Core of the Center for Clinical and Translational Sciences (CCTS). She is responsible for working with CCTS leadership and other CCTS core and program directors to coordinate the activities of the Biomedical Informatics Core with the broader CCTS program. In addition to directing operations for the BI Core, she directs the Core’s Clinical Research Data Resources program.

She also maintains a joint appointment as a research career scientist in the Department of Veterans Affairs, currently based at the Edward Hines Jr. VA Hospital. Dr. Hynes has developed and utilized databases and informatics throughout her health science research career. In her eleven years as director of the VA Information Resource Center (VIReC), she has overseen the development of data knowledge management expertise and resources, development of a research data warehouse that integrates VA and Medicare data, creation of a database and informatics helpdesk and consultation service, and the establishment of educational programs in database methods and clinical informatics.

Research Interests

Comparative effectiveness; economic burden of illness; health policy; quality of care for chronic disease management; informatics approaches, especially use of health information technology and clinical decision support systems to facilitate improvement in healthcare quality

Recent and Noteworthy Publications

For a more detailed list of publications by Dr. Denise Hynes, see this edited list on PubMed. 

Hynes DM, Fischer MJ, Schiffer LA, Gallardo R, Chukwudozie IB, Porter A, Berbaum M, Earheart J, Fitzgibbon ML. Evaluating a novel health system intervention for chronic kidney disease care using the RE-AIM framework: Insights after two years. Contemp Clin Trials. 2016 Oct 18;52:20-26. [See abstract.]

Porter AC, Fitzgibbon ML, Fischer MJ, Gallardo R, Berbaum ML, Lash JP, Castillo S, Schiffer L, Sharp LK, Tulley J, Arruda JA, Hynes DM. Rationale and design of a patient-centered medical home intervention for patients with end-stage renal disease on hemodialysis. Contemp Clin Trials. 2015 Feb 28;42:1-8. [See abstract.]

Weichle T, Hynes DM, Durazo-Arvizu R, Tarlov E, Zhang Q. Impact of alternative approaches to assess outlying and influential observations on health care costs. Springerplus. 2013 Nov 18;2:614. [See abstract.]

Hynes DM, Whittier ER, Owens A. Health information technology and implementation science: partners in progress in the VHA. Med Care. 2013 Mar;51 Suppl:S6-S12. [See abstract.]

Humensky JL, Jordan N, Stroupe KT, Hynes D. Employment status of veterans receiving substance abuse treatment from the u.s. Department of veterans affairs. Psychiatr Serv. 2013 Feb 1;64(2):177-80. [See abstract.]

Wang V, Maciejewski ML, Patel UD, Stechuchak KM, Hynes DM, Weinberger M. Comparison of outcomes for veterans receiving dialysis care from VA and non-VA providers. BMC Health Serv Res. 2013 Jan 18;13(1):26. [See abstract.]

Stroupe KT, Tarlov E, Lee TA, Weichle TW, Zhang QL, Michaelis LC, Ozer H, Durazo-Arvizu R, Browning MM, Hynes DM. Hemoglobin Levels Triggering Erythropoiesis-stimulating agent therapy in patients with cancer: the shift after United States Food and Drug Administration policy changes. Pharmacotherapy. 2012 Nov;32(11):988-97. [See abstract.]

Tarlov E, Lee TA, Weichle T, Durazo-Arvizu R, Zhang Q, Perrin R, Bentrem DJ, Hynes DM. Reduced overall and event-free survival among colon cancer patients using dual system care. Cancer Epidemiol Biomarkers Prev. 2012 Dec;21(12):2231-41. [See abstract.]

Tarlov E, Stroupe KT, Lee TA, Weichle TW, Zhang QL, Michaelis LC, Ozer H, Browning MM, Hynes DM. Trends in anemia management in lung and colon cancer patients in the US Department of Veterans Affairs, 2002-2008. Support Care Cancer. 2012 Aug;20(8):1649-57. [See abstract.]

Stroupe KT, Fischer MJ, Kaufman JS, O'Hare AM, Sohn MW, Browning MM, Huo Z, Hynes DM. Predialysis nephrology care and costs in elderly patients initiating dialysis. Med Care. 2011 Mar;49(3):248-56. [See abstract.]

Hynes DM, Stroupe KT, Fischer MJ, Reda DJ, Manning W, Browning MM, et al.; for ESRD Cost Study Group. Comparing VA and private sector healthcare costs for end-stage renal disease. Med Care. 2012 Feb;50(2):161-170.[See abstract.]

Saban KL, Bryant FB, Reda DJ, Stroupe KT, Hynes DM. Measurement invariance of the kidney disease and quality of life instrument (KDQOL-SF) across Veterans and non-Veterans. Health Qual Life Outcomes. 2010 Oct 25;8:120. [See abstract.]

Hynes DM, Tarlov E, Durazo-Arvizu R, Perrin R, Zhang Q, Weichle T, et al. Surgery and adjuvant chemotherapy use among veterans with colon cancer: insights from a California study. J Clin Oncol. 2010 May 20;28(15):2571-6.[See abstract.]

Fischer MJ, Stroupe KT, Kaufman JS, O'Hare AM, Browning MM, Huo Z, Hynes DM. Predialysis nephrology care among older veterans using department of veterans affairs or Medicare-covered services. Am J Manag Care. 2010 Feb 1;16(2):e57-66. [See abstract.]

Hynes DM, Weddle T, Smith N, Whittier E, Atkins D, Francis J. Use of health information technology to advance evidence-based care: lessons from the VA QUERI Program. J Gen Intern Med. 2010 Jan;25 Suppl 1:44-9. [See abstract.]

Saban, K, Sherwood, PR, DeVon, HA, Hynes, DM. Measures of Psychological Stress and Physical Health in Family Caregivers of Stroke Survivors: A Literature Review. Neuroscience Nursing. 2010; 42(3):128-38. [See abstract.]

Bentrem, DJ, Cohen ME, Hynes DM, Ko CY, Bilimoria KY. Identification of specific quality improvement opportunities for the elderly undergoing gastrointestinal surgery.  Arch Surg 2009; 144(11):1013-20. [See abstract.]

Hynes DM, Tarlov E, Lee T , Perrin R, Zhang Q, Ferreira MR, Durazo-Arvizo, R, Benson A., Bentrem, D, Bennett C, Examining disparities in colon cancer treatment patterns. J Clin Oncol, 2008 ASCO Annual Meeting Proceedings Part I. Vol 26, No. 15S (May 20 Supplement), 2008: 345s.[See abstract.]

Saban, K, Stroupe, KT,  Bryant, FB, Reda, D, Browning, MM, Huo, Z, and Hynes, DM. Comparison of Health-Related Quality of Life Measures for Chronic Renal Failure: Quality of Well-Being Scale, Short-Form-6D and the Kidney Disease Quality of Life Instrument. Quality of Life Research. 2008; 17(8): 1103-1115. [See abstract.]

Honors and Awards

IHRP Fellow
Fellow, ELAM Program of Drexel University, 2013–2014